Background:Head nurses in the Operating room are responsible for implementing and monitoring standards, which are crucial for ensuring quality medical care. The present study was conducted with the aim of investigating the impact of Quality Management Training on Compliance with Operating room standards.Methods:This interventional study was conducted in 2021 on 22 Operating room head nurses of Shiraz University of Medical Sciences hospitals selected by census method and randomly divided into two groups (14 intervention, 8 control). The data collection tool included a demographic information questionnaire and a checklist for checking equipment standards. The researcher taught the educational intervention in person (individually for each supervisor). Data were analyzed in SPSS-24 software using descriptive statistics (frequency, mean, standard deviation), Mann-Whitney U test, Kruskal-Wallis test, Spearman’s correlation test, Point-Biserial correlation test, and regression analysis.Results:The average age of the participants in the intervention group was 40.71 ± 5.26, and in the control group was 40.37 ± 2.61. The average level of adherence to the standards by the intervention group before the educational intervention was at a medium level (208.35 ± 20.37), and after receiving the educational intervention, it reached a high level (394.07 ± 2.464). There was a significant relationship between receiving the intervention of quality management training and the compliance of head nurses with Operating room standards (P<0.001). Conclusion:Considering the effect of educational intervention in improving compliance with Operating room standards, it is suggested that training courses be designed and implemented to maximize the level of awareness of Operating room head nurses.